Symbol
Name
ID

Ttc7
tetratricopeptide repeat domain 7
MGI:1920999

Phenotype annotations related to hematopoietic system

Darker colors indicate more annotations

Human Phenotypes	Decreased circulating antibody level	Agammaglobulinemia	Hematochezia	Autoimmune hemolytic anemia	Lymphopenia	Leukocytosis	Impaired lymphocyte transformation with phytohemagglutinin	Thrombocytosis	T-cell lymphoma
Disease(s) Associated with TTC7A
multiple intestinal atresia

Mouse Phenotypes

thymus cortex hypoplasia

decreased thymus weight

small thymus

enlarged spleen

increased spleen weight

abnormal definitive hematopoiesis

abnormal erythropoiesis

extramedullary hematopoiesis

anemia

decreased megakaryocyte cell number

erythroblastosis

abnormal erythrocyte morphology

abnormal erythrocyte cell number

increased fetal derived definitive erythrocyte cell number

low mean erythrocyte cell number

decreased hematocrit

decreased hemoglobin content

decreased mean corpuscular volume

increased nucleated erythrocyte cell number

anisocytosis

acanthocytosis

dacryocytosis

poikilocytosis

polychromatophilia

thrombocytosis

increased dendritic epidermal T cell number

increased leukocyte cell number

reticulocytosis

increased Langerhans cell number

increased spleen red pulp amount

decreased spleen white pulp amount

Availability

Mouse Genotype

Ttc7^fsn-Jic/Ttc7^fsn-Jic

Ttc7^fsn/Ttc7^fsn

Ttc7^hea/Ttc7^hea

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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